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Question 14 of 40 · Biochemistry
During the citric acid cycle, which enzyme catalyzes the conversion of isocitrate to α-ketoglutarate, producing CO₂ and NADH?
Biochemistry Hard
A Aconitase
B Succinate dehydrogenase
C Isocitrate dehydrogenase
D Citrate synthase
512
Projected MCAT score
🔥 14
Day study streak
3,200+
Practice questions
12k+
Students enrolled
515
Average score (Pro users)
4.9★
Student rating
Everything you need

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Biology Biochemistry General Chemistry Organic Chemistry Physics CARS Psychology Sociology
3,200+
Total questions
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CARS passages
3
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New questions added
Biology Hard
⏱ 1:42
A researcher discovers that a protein undergoes a conformational change only in the presence of both ATP and a specific lipid. This behavior is best described as which type of regulation?
A Competitive inhibition
B Covalent modification
C Allosteric regulation
D Feedback inhibition
Explanation
Allosteric regulation involves conformational changes induced by effector molecules (here, ATP + lipid acting together). This differs from covalent modification, which requires a chemical change to the protein itself. High-yield: know the difference between allosteric sites and active sites.
Study modules

Complete MCAT coverage

Four comprehensive modules, each packed with video lessons, concept sheets, and practice passages built around the AAMC content outline.

Bio / Biochem
Molecular biology, genetics, metabolism, enzymes, and cellular processes.
48 lessons · 820 questions
Chem / Physics
Gen chem, organic chemistry, physics, and lab techniques with worked examples.
52 lessons · 740 questions
CARS
Critical analysis, humanities and social science passages, argument mapping.
36 lessons · 480 passages
Psych / Soc
Psychology, sociology, behavioural science, and research methods.
40 lessons · 660 questions
Your performance overview
Last 30 days · 284 questions answered
Updated live
Bio/Biochem
132
Chem/Physics
128
CARS
127
Psych/Soc
130
Projected MCAT score
517
Top 96th percentile
Smart analytics

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Section score breakdown
Live scores per section plus sub-topic weak areas ranked by impact.
Score trend over time
See your improvement curve across weeks. Motivation built in.
AI score predictor Elite
Machine-learning model trained on thousands of student outcomes predicts your real MCAT score.
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"The CARS module alone was worth every penny. I went from consistently getting 125 to landing a 129 on test day. The passage practice is unlike anything else out there."

AM
Aisha M.
Vanderbilt School of Medicine
+12pts

"The analytics dashboard is genuinely brilliant. It told me I was weak on Chem/Physics stoichiometry and it was exactly right. I drilled that topic for two weeks and jumped 4 points in that section."

JP
James P.
University of Miami MD Program
+9pts

"I tried every MCAT platform. MCAT Mastery is the only one where I actually understood the explanations. The biochem module is incredibly detailed and the question quality is top tier."

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Sofia R.
NYU Grossman School of Medicine
+14pts
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FAQ

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No. MCAT Mastery is an independent study platform and is not affiliated with, endorsed by, or connected to the AAMC. We recommend using official AAMC practice tests alongside our platform for the best preparation.
How is this different from Khan Academy or UWorld?
MCAT Mastery combines a high-quality question bank with full study modules, live analytics, and an AI score predictor in one platform. Our CARS-specific content and analytics depth are particularly stronger than general study platforms.
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